The Salvation Army, Goodwill and other similar organizations might also accept the donation of your used mattress, and if so, you'll get the added perk of being able to claim the donation as a deduction on your income taxes. This is not a sure bet for getting rid of your mattress, however. It must be professionally cleaned and free of stains in order to be accepted. Still, many organizations won't accept mattresses no matter how well they've been maintained. You'll need to call your local donation center for more details, as these rules differ state by state. If you're lucky enough to find a center that accepts mattresses, be sure to ask them if they'll pick it up from your home, as the Goodwill and Salvation Army often offer free home pick-up for larger items.