We'll begin by admitting this oft-forgotten cleaning task is not fun, but ultimately, satisfying. No one looks forward to scrubbing the base of a toilet, but once you do, the entire bathroom will smell better. Plus, you'll foil the mildew having a house party on the toilet base right under your ... nose.
Start by using a disinfecting spray or undiluted white vinegar and dousing the base of the porcelain throne. Scrub the base, paying close attention to areas where the base meets the floor, and then dry with paper towels or an old towel you use only for cleaning. While you're at it, give the toilet handle a good spritz-and-scrub with a disinfectant.
Cleaning the toilet base every couple of weeks should suffice, but definitely consider disinfecting the toilet handle more often. The toilet is flushed before the hands are washed. Think about it [source: Design My Space].